Tuesday, 05 May 2015.
The disease is also known as a liver disease, which can be fatal if it does not work. According to the results of medical research, this disease affects one person’s estimate of every thirty thousand people. It is developed as a result of copper poisoning by cell and body organs. According to medical experts, the disease should be at an early stage, not wait until it reaches a lethal quantity. This disease usually affects bodies such as the liver and the brain. Under normal conditions, the body accumulates a surplus of copper than it can actually hold, which results in an attack on these sensitive bodies. The presence of copper in the brain and liver can lead to serious medical conditions that require immediate intervention, otherwise life may be lost. The Med belongs to the category of trace elements that are required for the body in small quantities to perform various biological operations. However, most of the elements should be released through body cells and screens
It is a concept that helps distinguish ordinary people from those who suffer from Wilson’s disease, because they are usually unable to dissuade excessive copper connections from their bodies. As mentioned earlier, this state of health is genetic and is caused by the excessive accumulation of copper in the body that ultimately attacks vital organs. The presence of this disease has been found since the birth of the child, and the patient develops the identity in terms of physical and psychological behavior (Sang, Hee, Sun Ho & Dae Ghon, 2013, p. 500). Excessive copper in the body creates conditions in which the body can deteriorate, and mainly ends in the event of death if not to take part in the work. Symptoms of this state are evident in the liver from birth, but it is more pronounced during adolesage. At this point, the excess of copper in the body starts to acquire a new state and therefore has a negative impact on the liver. The condition of the liver can only be seen through microscopes, and the physical state of the liver is determined on the basis of that condition
Causes and inheritance of Wilson’s disease
The cause of Wilson’s disease is directly related to the failure of a certain gene found in a chromosome. The failure in gene 13 is something that leads to serious symptoms that were subsequently turned into Wilson’s disease. This gene is commonly referred to as ATP7B, and is primarily intended for managing the levels of copper in body bodies. If the gene does not function as needed, it will be among the first to be affected. As a result, copper is at a low level, resulting in the accumulation of bile bile in the liver. It could be a death. Excess layers that have high levels of copper in the liver, as well as copper seep compounds away from the liver in the bloodstream and finally into the brain. As soon as the copper elements get into the brain, the condition of the body is deteriorating. On the basis of the poisonous nature of these compounds, they usually pose a great danger to the bodies of the body
This disease is inherited according to the composition and alignment of genes. The condition is an automatic recessive disorder. This term is associated with inheritance genates. For example, a person develops Wilson’s disease after inheriting two of the ATP7B anomalies in the body. This pair of anomalous genes comes from both parents; father and mother (Tamura, Sugawara, Kishi, Hamamatsu, Kaneko & Makuchi, 2005, 485). The simplest explanation for this disease can best be shown in the diagram. Based on this gene diagram, both parents must be Wilson’s disease, and the genetic combination must be that a couple of abnormal genes forms the genetic makeup of a child
The succession of one abnormal gene by an individual means that it becomes a carrier. Carriers do not have a disease because one of their genes has the ability to control copper in the organs. However, two carriers have a higher chance of handing over the riots to their children. These cases are inadvertently established and take place only in special circumstances. According to Wilson’s disease control statistics, there is one case of disease in every 100 people. In cases where two persons with abnormal genes have a child, this affects certain conditions
In another case, the child has neither a disorder nor a carrier. This means that a born child will not suffer from a defect of her parents. This is rare, as it can only be one of the four possible options. In this case, descendants inherit normal genes, so they are free from state. The discussion of the question of the appearance and consequences of the child is, in fact, behind all genetic diseases
Symptoms of this disorder may be lost over a period of six years in some people, as well as for more than forty years. However, there are certain cases in which the symptoms of leenage occur. Despite all this, Wilson’s disease is an inalienable human right since birth. Symptoms vary according to which target authorities are attacked and the development stage. The first category of symptoms is affected by the liver attack. The liver is starting to create problems when the liver is inflated. Toxic elements of the media make this body swelling into the liver. This condition is commonly referred to as hepatitis or liver inflammation. Hepatitis is a mild condition, but may result in the loss of body parts. For example, the presence of hepatitis could lead to unfavourable conditions such as jaundice, vomiting and severe abdominal pain. If this situation persists in the liver, it may cause other effects such as liver damage called cirrhosis (Brewer, 2005, p. 187). These problems can further affect unrecoverable situations and typically result in liver failure
There is also another problem, which is a serious case of excessive concentration in the liver. With limited control of copper in the form of bile, the elements soak into the bloodstream, where they are in the brain. The presence of mobile in the brain can lead to adverse results that may result in physical impurity. For example, the victim may experience tremors in the hands, a general slowing of speech, difficulties in the throat of food and, in extreme cases, the absence of saliva. Other symptoms of a mobile presence in the brain include erring walking, appallation and problems in writing
These physical problems can torture patients psychologically and even in the event of psychological trauma. Some of the symptoms of psychological symptoms include depression, mood swings and the inability of the individual to focus on his actions. Such symptoms have transformed the human person into argument and sometimes even developed strong emotional responses and vulnerabilities. The poor state of self-control is one of the reasons for Wilson’s disorder at a later stage. At this point, a high concentration of mobile in the brain can lead to serious conditions if they are not addressed in time. For example, the constant accumulation of copper in the brain may become a chronic condition, which causes a strong weakness in the muscle, the development of dementia and the excessive stiffness of body organs and even connections
In addition, copper in the liver may also be transferred to other bodies of the body. For example, the excessive concentration of copper in the eyes may lead to a superannic and characteristic feature known as the Kayser-Fleischer rings (Svetel, Pekmezovic, Petrovitz, Tic, Kreojevic, Jesic & Kostic, 2009, p. 855). This can be presented in the form of brownish pigment in horny. The secondary effects of the accumulation of excess copper are not limited only to the symptoms mentioned above, but also apply to other body problems such as pancreatitis, kidney damage, anaemia, heart problems, menstruation defects among others, such as carriages in women
Wilson’s disease diagnosis
There are many ways to diagnose Wilson’s disorder to make sure that his presence in the body is determined and precise. This entails managing multiple tests that differ in the level of suspicion and prevalence. The first test is run through blood tests to measure the element known as caeruplmin. An element is a common factor, the role of which is the binding of copper in human blood. The body’s ability to have discrete excess copper is determined by the level of caeruplasmin. Under normal conditions of body, high levels of content are ideal. People with lower levels of this disease are severely affected by Wilson’s disease
Blood tests will help you set the number of caeruplaspmin in the body. It’ll figure out if he’s got a violation or not. The test is part of the most effective way to determine Wilson’s disease in his body. When measuring a protein that links copper in the blood, it is made at the level of the disorder (Da Silva-Junior, Carrasco, Mendes, A Lopes & De Bruin, 2008). In addition, very low levels of caeruplasmin are associated with the high rate of copper loss and hence adverse conditions. In addition to blood tests, there are also other tests that are also conducted to determine the levels of copper in the body. For example, there may be other tests on the kidney and liver
These organs are the most vulnerable to Wilson’s disease, and the tests they do can provide the appropriate states. In addition, it is possible to conduct a hepatitis test among other infections to determine whether these bodies are affected or not. During the examination of a kidney during a brief examination, detailed information about her condition in relation to this disorder is given. The infection is equally affecting the kidneys, and sometimes they may not even perform their functions effectively in attacking Wilson’s disease
Another test that can also be tested to determine if he has a urine test. The ortinin test can be used as the most viable means to determine the contents of copper in the body. For example, the optimum levels of copper in urine are converted into a high or abnormal presence of Wilson’s disease. According to the results of the test, low copper levels in the urine can lead to a lot of copper copper in the kidney which can cause serious kidney damage
In addition, the high level of copper in urine may also mean the concentration of copper in the body. This test is carried out in all urine produced by a person in one day. This violation can be determined by the presence of the Kayer-Fleischer ring. Based on this test, the horny eyes are checked by a specialist in optok or eye. In addition, appropriate tests can be conducted to determine the level of copper and the extent of the infection. One of these tests is known as a biopsy, which involves studying liver samples under a microscope. The results of this test will indicate the scale of cirrhosis and copper in the liver
A specialist can also request other important tests such as MRI scans and kidneys. These tests may increase the degree of damage to the towing bodies (Merle, Weiss, Eisenbach, Tuma, S Ferenci & Stimmel, 2010, p. 108). The MRI views provide detailed information about the brain’s condition due to the influence of copper deposits. The confirmation of the violation in the body should be supplemented by other secondary tests for the individual brothers and sisters. Medical research shows that the victim’s brothers and sisters have one of four chances for the disease. With this information, doctors can make general conclusions that they should have broader prospects for Wilson. On the basis of this probabilistic cycle, at least one or more of the victims ‘ brothers are carriers
The treatment of Wilson’s disease
This disease affects the brain and liver, respectively, and thus, in order to mitigate the effects of the disease. The first set of treatments is oral drug overdose. Penicillamine is one of the drugs that can be used to reduce the level of copper in the body. This drug may shoot down copper levels that are related to liver failure to control and support the body of Ph. When this drug is taken, it ensures that the excess of copper is removed from the body in the form of urine. The administration of the penici may significantly reduce the concentration of copper in the blood. For example, it is reduced when the copper build in the body is less. This drug is a necessary preventive measure and should be used for up to one year. Apart from penicillin, copper in the body may also be reduced through the Trientine administration. It is a medicine that helps remove the excess concentration of copper from the body (Okada, Shiono, Kaneko, Miwa & Yamagishi, 2010, p. 1238).
Wilson’s disease can be processed in several ways, which may also include the introduction of zinc in the body. The presence of zinc in the body is crucial, as it contributes to the blocking of the geese by the absorption of copper, which may affect excessive quantities in the body. Zinc plays a preventive role by blocking the bowel, preying on further accumulation of copper in body organs. In addition to protection from intestines, zinc has another advantage over the penicimas and trientinis, as it does not show any side effects after use. Zinc has a moderate effect on the body and usually does not have a negative impact on normal body operations. The zinc cap is linked to the state of early signs of the disease. In the early stages of spreading the infection can be prevented with zinc. Another case where zinc is also appropriate is that the victim was originally processed using the Penicillamine or Trientine, and the accumulation of copper in the body has already begun. Zinc is also ideal for pregnant women, as it helps in the right development of the foetus
Bolotnaya disorder is very dangerous for the normal functioning of the body, and processing of life is considered the most viable way to get out of this effect. This process is performed in sequences and begins with the cleaning of redundant copper in the body before starting to work with the mechanisms to stop further accumulation. Preventive measures can eliminate the possibility of a repeated accumulation of copper in the body, fully controlling the future of the accident. Other cases may result in death, especially if they are identified at a later stage of the infection. Such adverse conditions or damage to organs may sometimes fail to respond to treatment through medicines. Thus, the ideal treatment is organ transplantation, which happens in circumstances where the organs are completely damaged
For example, liver elimination requires liver transplantation to serve the liver in the human body. However, this method is very costly, since many cannot afford it. Another simple means of ensuring the stability of the body is the proper diet. The right to food helps the victim to keep himself safe from food-related conditions that may worsen the physical body. Recommended diets should not contain copper rich products that can increase copper in the body (Martin, Bartels, Redlich, Hauss & Fangmann, 2008, p. 218). Every effort is aimed at reducing the level of copper in the body, which can be achieved by eating food with low copper content. Some of the main products to be avoided include liver, nuts, chocolate, beans, mushrooms, shellfish and lobster. It is very important for the person to eat the appropriate diet and take the right food to control the violation
In conclusion, Wilson’s disease is a serious disease that requires careful diagnosis and treatment. If one is perfect, the impact on the body will remain low. Early treatments are ideal for controlling and preventing future treatment. This concept is the control version of the control of the disorder
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Tamura, S., Sugawara, Y., Kishi, Y., Hamamatsu, N., Kaneko, J., & Makuuchi, M. (2005): liver transplantation due to Wilson’s disease